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Toeeei Adrenal crisis occurs when The adrenal gland is damaged Addisons disease primary adrenal insufficiency The pituitary gland is injured secondary adrenal insufficiency and it cannot release ACTH Adrenal insufficiency is not properly treated Risk factors for adrenal crisis include Dehydration Infection and other physical stress Injury to the adrenal or pituitary gland Stopping treatment with steroids such as prednisone or hydrocortisone quickly or too early Surgery Trauma Symptoms Abdominal pain Confusion or coma Darkening of the skin Dehydration Dizziness or lightheadedness Fatigue Flank pain Headache High fever Joint pain Loss of appetite Loss of consciousness Low blood pressure Nausea Profound weakness Rapid heart rate Rapid respiratory rate see tachypnea Shaking chills Skin rash or lesions Slow sluggish movement Unintentional weight loss Unusual and excessive sweating on face or palms Vomiting Exams and Tests ACTH cosyntropin stimulation test Cortisol level Fasting blood sugar Serum potassium Serum sodium Treatment In adrenal crisis patients need an immediate injection of hydrocortisone through a vein intravenous or muscle intramuscular. is prednisone from overseas safe